| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-glucosidase |
|---|
| Ligand | BDBM50451727 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1746126 (CHEMBL4180636) |
|---|
| IC50 | 89420±n/a nM |
|---|
| Citation |  Lawande, PP; Sontakke, VA; Kumbhar, NM; Bhagwat, TR; Ghosh, S; Shinde, VS Polyhydroxylated azetidine iminosugars: Synthesis, glycosidase inhibitory activity and molecular docking studies. Bioorg Med Chem Lett27:5291-5295 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-glucosidase |
|---|
| Name: | Alpha-glucosidase |
|---|
| Synonyms: | AGLU_ASPNG | aglA |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 108889.92 |
|---|
| Organism: | Aspergillus niger |
|---|
| Description: | ChEMBL_974466 |
|---|
| Residue: | 985 |
|---|
| Sequence: | MVKLTHLLARAWLVPLAYGASQSLLSTTAPSQPQFTIPASADVGAQLIANIDDPQAADAQ
SVCPGYKASKVQHNSRGFTASLQLAGRPCNVYGTDVESLTLSVEYQDSDRLNIQILPTHV
DSTNASWYFLSENLVPRPKASLNASVSQSDLFVSWSNEPSFNFKVIRKATGDALFSTEGT
VLVYENQFIEFVTALPEEYNLYGLGEHITQFRLQRNANLTIYPSDDGTPIDQNLYGQHPF
YLDTRYYKGDRQNGSYIPVKSSEADASQDYISLSHGVFLRNSHGLEILLRSQKLIWRTLG
GGIDLTFYSGPAPADVTRQYLTSTVGLPAMQQYNTLGFHQCRWGYNNWSDLADVVANFEK
FEIPLEYIWTDIDYMHGYRNFDNDQHRFSYSEGDEFLSKLHESGRYYVPIVDAALYIPNP
ENASDAYATYDRGAADDVFLKNPDGSLYIGAVWPGYTVFPDWHHPKAVDFWANELVIWSK
KVAFDGVWYDMSEVSSFCVGSCGTGNLTLNPAHPSFLLPGEPGDIIYDYPEAFNITNATE
AASASAGASSQAAATATTTSTSVSYLRTTPTPGVRNVEHPPYVINHDQEGHDLSVHAVSP
NATHVDGVEEYDVHGLYGHQGLNATYQGLLEVWSHKRRPFIIGRSTFAGSGKWAGHWGGD
NYSKWWSMYYSISQALSFSLFGIPMFGADTCGFNGNSDEELCNRWMQLSAFFPFYRNHNE
LSTIPQEPYRWASVIEATKSAMRIRYAILPYFYTLFDLAHTTGSTVMRALSWEFPNDPTL
AAVETQFMVGPAIMVVPVLEPLVNTVKGVFPGVGHGEVWYDWYTQAAVDAKPGVNTTISA
PLGHIPVYVRGGNILPMQEPALTTREARQTPWALLAALGSNGTASGQLYLDDGESIYPNA
TLHVDFTASRSSLRSSAQGRWKERNPLANVTVLGVNKEPSAVTLNGQAVFPGSVTYNSTS
QVLFVGGLQNLTKGGAWAENWVLEW
|
|
|
|---|
| BDBM50451727 |
|---|
| n/a |
|---|
| Name | BDBM50451727 |
|---|
| Synonyms: | CHEMBL4218600 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C5H11NO3 |
|---|
| Mol. Mass. | 133.1457 |
|---|
| SMILES | OC[C@H]1N[C@@H](CO)[C@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
