| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50019457 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_38486 (CHEMBL652396) |
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| IC50 | >10000±n/a nM |
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| Citation |  Wise, LD; Butler, DE; DeWald, HA; Lustgarten, D; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA (5-Amino-1,3-dimethyl-1H-pyrazol-4-yl)(2-fluorophenyl)methanones . A series of novel potential antipsychotic agents. J Med Chem29:1628-37 (1986) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2_RAT | Adrb2 | Adrb2r | Adrenergic receptor beta |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46896.26 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_38603 |
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| Residue: | 418 |
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| Sequence: | MEPHGNDSDFLLAPNGSRAPGHDITQERDEAWVVGMAILMSVIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWNFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYVAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHKQ
AIDCYAKETCCDFFTNQAYAIASSIVSFYVPLVVMVFVYSRVFQVAKRQLQKIDKSEGRF
HAQNLSQVEQDGRSGHGLRSSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIRA
NLIPKEVYILLNWLGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSSKTYGNGYSSNSNG
RTDYTGEQSAYQLGQEKENELLCEEAPGMEGFVNCQGTVPSLSIDSQGRNCNTNDSPL
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|
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| BDBM50019457 |
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| n/a |
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| Name | BDBM50019457 |
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| Synonyms: | 2-Diethylamino-N-[4-(2-fluoro-benzoyl)-2,5-dimethyl-2H-pyrazol-3-yl]-acetamide | CHEMBL42084 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H23FN4O2 |
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| Mol. Mass. | 346.3992 |
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| SMILES | CCN(CC)CC(=O)Nc1c(C(=O)c2ccccc2F)c(C)nn1C |
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| Structure | 
|
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