| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP4 subtype |
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| Ligand | BDBM50138052 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1751766 (CHEMBL4186526) |
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| EC50 | 339±n/a nM |
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| Citation |  Kinoshita, A; Higashino, M; Yoshida, K; Aratani, Y; Kakuuchi, A; Hanada, K; Takeda, H; Naganawa, A; Matsuya, H; Ohmoto, K Synthesis and evaluation of a potent, well-balanced EP Bioorg Med Chem26:200-214 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP4 subtype |
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| Name: | Prostaglandin E2 receptor EP4 subtype |
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| Synonyms: | PE2R4_HUMAN | PGE receptor EP4 subtype | PGE2 receptor EP4 subtype | PTGER2 | PTGER4 | Prostaglandin E2 receptor | Prostanoid EP4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 53134.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35408 |
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| Residue: | 488 |
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| Sequence: | MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCG
LAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLA
INHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTA
HAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRG
HPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP
SLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSG
QHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPG
MGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSET
LNLSEKCI
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| BDBM50138052 |
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| n/a |
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| Name | BDBM50138052 |
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| Synonyms: | CHEMBL3751951 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H27FN2O5S2 |
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| Mol. Mass. | 458.567 |
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| SMILES | O[C@H](\C=C\[C@H]1COC(=O)N1CCSc1nc(cs1)C(O)=O)C1(CCCCF)CCC1 |r| |
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| Structure | 
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