| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin E2 receptor EP1 subtype |
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| Ligand | BDBM50454060 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1751788 (CHEMBL4186548) |
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| EC50 | 2000±n/a nM |
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| Citation |  Kinoshita, A; Higashino, M; Yoshida, K; Aratani, Y; Kakuuchi, A; Hanada, K; Takeda, H; Naganawa, A; Matsuya, H; Ohmoto, K Synthesis and evaluation of a potent, well-balanced EP Bioorg Med Chem26:200-214 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Prostaglandin E2 receptor EP1 subtype |
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| Name: | Prostaglandin E2 receptor EP1 subtype |
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| Synonyms: | PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41834.57 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34995 |
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| Residue: | 402 |
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| Sequence: | MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
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| BDBM50454060 |
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| n/a |
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| Name | BDBM50454060 |
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| Synonyms: | CHEMBL4208379 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H31NO4S2 |
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| Mol. Mass. | 437.616 |
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| SMILES | C[C@@](O)(C\C=C\[C@H]1CCC(=O)[C@@H]1CCSc1nc(cs1)C(O)=O)CC1CCCC1 |r| |
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| Structure | 
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