| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 5B, mitochondrial |
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| Ligand | BDBM50454306 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1752588 (CHEMBL4187348) |
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| Kd | 0.780000±n/a nM |
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| Citation |  ?apkauskait?, E; Zak?auskas, A; Ruibys, V; Linkuvien?, V; Paketuryt?, V; Gedgaudas, M; Kairys, V; Matulis, D Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors. Bioorg Med Chem26:675-687 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 5B, mitochondrial |
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| Name: | Carbonic anhydrase 5B, mitochondrial |
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| Synonyms: | CA-VB | CA5B | CAH5B_HUMAN | Carbonate dehydratase VB | Carbonic Anhydrase VB | Carbonic anhydrase 5B (CA VB) | Carbonic anhydrase 5B, mitochondrial | Carbonic anhydrase 5B, mitochondrial precursor | Carbonic anhydrase V | Carbonic anhydrase VB (CA VB) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36440.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human (cloned) isozyme |
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| Residue: | 317 |
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| Sequence: | MVVMNSLRVILQASPGKLLWRKFQIPRFMPARPCSLYTCTYKTRNRALHPLWESVDLVPG
GDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGGPL
EHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLAVI
GVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLMPTCPDYWTYSGSLTTPPLS
ESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSFRHDY
VLNVQAKPKPATSQATP
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| BDBM50454306 |
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| n/a |
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| Name | BDBM50454306 |
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| Synonyms: | CHEMBL4218335 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H15ClN4O3S2 |
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| Mol. Mass. | 458.941 |
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| SMILES | NS(=O)(=O)c1cc(C(=O)Nn2cnc3ccccc23)c(Sc2ccccc2)cc1Cl |
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| Structure | 
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