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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fatty-acid amide hydrolase 1 | ||
| Ligand | BDBM50454598 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1752866 (CHEMBL4187626) | ||
| IC50 | 24±n/a nM | ||
| Citation |  Kodani, SD; Bhakta, S; Hwang, SH; Pakhomova, S; Newcomer, ME; Morisseau, C; Hammock, BD Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorg Med Chem Lett28:762-768 (2018) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fatty-acid amide hydrolase 1 | |||
| Name: | Fatty-acid amide hydrolase 1 | ||
| Synonyms: | Anandamide amidohydrolase | Anandamide amidohydrolase 1 | FAAH | FAAH1 | FAAH1_HUMAN | Fatty Acid Amide Hydrolase (FAAH) | Fatty-acid amide hydrolase (FAAH) | Fatty-acid amide hydrolase 1 | Oleamide hydrolase 1 | ||
| Type: | Protein | ||
| Mol. Mass.: | 63071.19 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O00519 | ||
| Residue: | 579 | ||
| Sequence: |
| ||
| BDBM50454598 | |||
| n/a | |||
| Name | BDBM50454598 | ||
| Synonyms: | CHEMBL4215208 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H27F3N2O5 | ||
| Mol. Mass. | 528.5196 | ||
| SMILES | FC(F)(F)Oc1ccc(NC(=O)N[C@H]2CC[C@@H](CC2)Oc2ccc(cc2)C(=O)OCc2ccccc2)cc1 |r,wU:16.19,wD:13.12,(30.34,-3.34,;30.34,-4.74,;31.59,-3.72,;29.09,-3.72,;30.34,-6.28,;31.68,-7.05,;31.67,-8.59,;33.01,-9.36,;34.35,-8.59,;35.68,-9.36,;37.01,-8.59,;37.01,-7.05,;38.35,-9.35,;39.68,-8.58,;41.01,-9.36,;42.34,-8.59,;42.34,-7.05,;41.01,-6.28,;39.67,-7.05,;43.68,-6.28,;45.01,-7.06,;45,-8.6,;46.33,-9.37,;47.67,-8.6,;47.67,-7.05,;46.34,-6.29,;49,-9.37,;49,-10.91,;50.34,-8.6,;51.67,-9.38,;53,-8.61,;54.33,-9.38,;55.67,-8.61,;55.67,-7.07,;54.33,-6.3,;53,-7.07,;34.34,-7.04,;33.01,-6.28,)| | ||
| Structure | 
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