| Reaction Details |
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 | Report a problem with these data |
| Target | Midkine |
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| Ligand | BDBM50454863 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1753624 (CHEMBL4188384) |
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| IC50 | 396±n/a nM |
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| Citation |  Maza, S; Gandia-Aguado, N; de Paz, JL; Nieto, PM Fluorous-tag assisted synthesis of a glycosaminoglycan mimetic tetrasaccharide as a high-affinity FGF-2 and midkine ligand. Bioorg Med Chem26:1076-1085 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Midkine |
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| Name: | Midkine |
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| Synonyms: | ARAP | Amphiregulin-associated protein | MDK | MK | MK1 | MK_HUMAN | Midgestation and kidney protein | NEGF2 | Neurite outgrowth-promoting factor 2 | Neurite outgrowth-promoting protein |
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| Type: | PROTEIN |
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| Mol. Mass.: | 15605.71 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_805023 |
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| Residue: | 143 |
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| Sequence: | MQHRGFLLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSKDCGVGFREGT
CGAQTQRIRCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQGTLKKARYNAQCQETI
RVTKPCTPKTKAKAKAKKGKGKD
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| BDBM50454863 |
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| n/a |
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| Name | BDBM50454863 |
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| Synonyms: | CHEMBL4206352 |
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| Type | Small organic molecule |
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| Emp. Form. | C57H50F17NO23S2 |
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| Mol. Mass. | 1504.103 |
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| SMILES | COc1ccc(O[C@@H]2O[C@H](COC(=O)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)[C@@H](O[C@@H]3O[C@H](COS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@H](OC(=O)CCC(C)=O)[C@H]3N3C(=O)c4ccccc4C3=O)[C@H](OCc3ccccc3)[C@H]2OC(=O)c2ccccc2)cc1 |r| |
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| Structure | 
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