| Reaction Details |
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 | Report a problem with these data |
| Target | Cytosol aminopeptidase |
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| Ligand | BDBM50457469 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1759813 (CHEMBL4194821) |
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| Ki | 1300±n/a nM |
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| Citation |  Amin, SA; Adhikari, N; Jha, T Design of Aminopeptidase N Inhibitors as Anti-cancer Agents. J Med Chem61:6468-6490 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytosol aminopeptidase |
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| Name: | Cytosol aminopeptidase |
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| Synonyms: | AMPL_HUMAN | Aminopeptidase | LAP3 | LAPEP | Leucine aminopeptidase | PEPS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56171.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507539 |
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| Residue: | 519 |
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| Sequence: | MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFD
KLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKEN
IRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGS
GDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWI
EEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMD
LMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQV
DNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFE
ASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL
DIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA
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| BDBM50457469 |
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| n/a |
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| Name | BDBM50457469 |
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| Synonyms: | CHEMBL4213478 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H24BNO2 |
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| Mol. Mass. | 213.125 |
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| SMILES | CC(C)CC(N)B1OC(C)(C)C(C)(C)O1 |
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| Structure | 
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