| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit gamma-2 |
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| Ligand | BDBM50229715 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1767516 (CHEMBL4219628) |
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| EC50 | >50000±n/a nM |
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| Citation |  Sparling, BA; DiMauro, EF Progress in the discovery of small molecule modulators of the Cys-loop superfamily receptors. Bioorg Med Chem Lett27:3207-3218 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gamma-aminobutyric acid receptor subunit gamma-2 |
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| Name: | Gamma-aminobutyric acid receptor subunit gamma-2 |
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| Synonyms: | GABA(A) receptor subunit gamma-2 | GBRG2_MOUSE | Gabrg2 | Gamma-aminobutyric acid receptor subunit gamma-2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55110.97 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_118290 |
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| Residue: | 474 |
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| Sequence: | MSSPNTWSIGSSVYSPVFSQKMTLWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKV
PEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTW
YDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYT
LRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFS
FVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAV
PARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVS
NRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKD
CASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL
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| BDBM50229715 |
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| n/a |
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| Name | BDBM50229715 |
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| Synonyms: | CHEMBL4070615 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19N3O5S |
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| Mol. Mass. | 401.436 |
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| SMILES | [H][C@]12CN([C@@H](C)[C@@]1([H])C(=O)N(C)c1ccncc21)S(=O)(=O)c1ccc2OCOc2c1 |r| |
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| Structure | 
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