| Reaction Details |
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 | Report a problem with these data |
| Target | Chymotrypsinogen A |
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| Ligand | BDBM50462115 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1772760 (CHEMBL4229752) |
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| Ki | 107±n/a nM |
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| Citation |  Ramesh, R; Reddy, DS Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds. J Med Chem61:3779-3798 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymotrypsinogen A |
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| Name: | Chymotrypsinogen A |
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| Synonyms: | Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin) |
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| Type: | Serine protease |
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| Mol. Mass.: | 25670.88 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 245 |
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| Sequence: | CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGV
TTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSA
VCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAM
ICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQ
TLAAN
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| BDBM50462115 |
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| n/a |
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| Name | BDBM50462115 |
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| Synonyms: | CHEMBL2311598 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H27N3O4Si |
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| Mol. Mass. | 365.4995 |
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| SMILES | [#6]-[#6@H](-[#6][Si;v4]([#8])([#8])[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1)-[#6](-[#7])=O |r| |
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| Structure | 
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