| Reaction Details |
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 | Report a problem with these data |
| Target | Neuraminidase |
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| Ligand | BDBM50464876 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1783267 (CHEMBL4254784) |
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| IC50 | 590±n/a nM |
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| Citation |  Wang, PC; Chiu, DC; Jan, JT; Huang, WI; Tseng, YC; Li, TT; Cheng, TJ; Tsai, KC; Fang, JM Peramivir conjugates as orally available agents against influenza H275Y mutant. Eur J Med Chem145:224-234 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuraminidase |
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| Name: | Neuraminidase |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 51689.62 |
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| Organism: | Influenza A virus (A/Brisbane/59/2007(H1N1)) |
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| Description: | D5F1R0 |
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| Residue: | 470 |
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| Sequence: | MNPNQKIITIGSISIAIGIISLMLQIGNIISIWASHSIQTGSQNNTGICNQRIITYENST
WVNHTYVNINNTNVVAGEDKTSVTLAGNSSLCSISGWAIYTKDNSIRIGSKGDVFVIREP
FISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRALMSCPLGEAPSPYNSKFESVAWS
ASACHDGMGWLTIGISGPDNGAVAVLKYNGIITGTIKSWKKQILRTQESECVCMNGSCFT
IMTDGPSNKAASYKIFKIEKGKVTKSIELNAPNFHYEECSCYPDTGIVMCVCRDNWHGSN
RPWVSFNQNLDYQIGYICSGVFGDNPRPEDGEGSCNPVTVDGANGVKGFSYKYDNGVWIG
RTKSNRLRKGFEMIWDPNGWTNTDSDFSVKQDVVAITDWSGYSGSFVQHPELTGLDCIRP
CFWVELVRGLPRENTTIWTSGSSISFCGVNSDTANWSWPDGAELPFTIDK
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| BDBM50464876 |
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| n/a |
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| Name | BDBM50464876 |
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| Synonyms: | CHEMBL4288995 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H41N5O9 |
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| Mol. Mass. | 591.6532 |
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| SMILES | [H][C@]1([C@@H](NC(C)=O)C(CC)CC)[C@@H](C[C@@H]([C@H]1OC(=O)NCCCOC(=O)\C=C\c1ccc(O)c(O)c1)C(O)=O)NC(N)=N |r| |
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| Structure | 
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