| Reaction Details |
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 | Report a problem with these data |
| Target | Transcriptional activator protein LasR |
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| Ligand | BDBM50465698 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1788567 (CHEMBL4260301) |
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| IC50 | 3270±n/a nM |
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| Citation |  Soukarieh, F; Williams, P; Stocks, MJ; Cámara, M Pseudomonas aeruginosa Quorum Sensing Systems as Drug Discovery Targets: Current Position and Future Perspectives. J Med Chem61:10385-10402 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transcriptional activator protein LasR |
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| Name: | Transcriptional activator protein LasR |
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| Synonyms: | LASR_PSEAE | lasR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26618.24 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | ChEMBL_1475312 |
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| Residue: | 239 |
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| Sequence: | MALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAW
REHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHG
ARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSR
EKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL
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| BDBM50465698 |
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| n/a |
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| Name | BDBM50465698 |
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| Synonyms: | CHEMBL3403857 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H18N4O3 |
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| Mol. Mass. | 266.2963 |
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| SMILES | CCCCc1cn(CC(=O)N[C@H]2CCOC2=O)nn1 |r| |
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| Structure | 
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