| Reaction Details |
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 | Report a problem with these data |
| Target | Aldehyde dehydrogenase 1A1 |
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| Ligand | BDBM50466622 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1793467 (CHEMBL4265386) |
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| Ki | 194±n/a nM |
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| Citation |  Harper, AR; Le, AT; Mather, T; Burgett, A; Berry, W; Summers, JA Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes. Bioorg Med Chem26:5766-5779 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aldehyde dehydrogenase 1A1 |
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| Name: | Aldehyde dehydrogenase 1A1 |
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| Synonyms: | 1.2.1.- | 1.2.1.36 | AL1A1_CHICK | ALDH1A1 | Aldehyde dehydrogenase, cytosolic | RALDH 1 | RalDH1 | Retinal dehydrogenase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55813.22 |
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| Organism: | Gallus gallus |
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| Description: | ChEMBL_117982 |
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| Residue: | 509 |
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| Sequence: | MKKQGSPSNPAPVLPALPEPLKDLKIKYTKIFINNEWHDSVSGKKFEVFNPANEEKICEV
AEGDKADIDKAVKAARKAFELGSPWRTMDASERGRLLNKLADLVERDRLTLATMEAIDGG
KLFSTAYLMDLGACIKTIRYCAGWADKIHGRTVPMDGNFFTFTRHEPVGVCGQIIPWNFP
LVMFIWKIAPALCCGNTVVVKPAEQTPLSALYMGSLIKEAGFPPGVVNIVPGFGPTAGAA
ISHHMDIDKVSFTGSTEVGKLIKEAAGKTNLKRVTLELGGKSPNIIFADADLDEAAEFAH
IGLFYHQGQCCIAGSRIFVEEPIYDEFVRRSIERAKKYTLGDPLLPGVQQGPQIDKEQFQ
KILDLIESGKKEGAKLECGGGPWGNKGYFIQPTVFSNVTDDMRIAKEEIFGPVQQIMKFK
TIDEVIKRANNTTYGLAAAVFTKDIDKALTFASALQAGTVWVNCYSAFSAQCPFGGFKMS
GNGRELGEYGLQEYTEVKTVTIKIPQKNS
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| BDBM50466622 |
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| n/a |
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| Name | BDBM50466622 |
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| Synonyms: | CHEMBL4286209 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H28Cl2O |
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| Mol. Mass. | 367.352 |
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| SMILES | C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)C(Cl)Cl |c:4| |
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| Structure | 
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