| Reaction Details |
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 | Report a problem with these data |
| Target | Retinal dehydrogenase 2 |
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| Ligand | BDBM50459608 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1793494 (CHEMBL4265413) |
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| EC50 | 44±n/a nM |
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| Citation |  Harper, AR; Le, AT; Mather, T; Burgett, A; Berry, W; Summers, JA Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes. Bioorg Med Chem26:5766-5779 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinal dehydrogenase 2 |
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| Name: | Retinal dehydrogenase 2 |
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| Synonyms: | 1.2.1.36 | AL1A2_CHICK | ALDH1A2 | Aldehyde dehydrogenase family 1 member A2 | RALDH 2 | RALDH(II) | RALDH2 | Retinal dehydrogenase 2 | Retinaldehyde-specific dehydrogenase type 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56729.31 |
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| Organism: | Gallus gallus |
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| Description: | ChEMBL_117928 |
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| Residue: | 518 |
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| Sequence: | MTSSKIEMPGEVKADPAALMASLHLLPSPTLNLEIKHTKIFINNEWQNSESGRVFPVYNP
ATGEQICEIQEADKVDTDKAVRAARLAFSLGSVWRRMDASERGQLLDKLADLVERDRAVL
ATMESLNSGKPFLQAFYVDLQGVIKTLRYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVC
GQIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQTPLSALYMGALIKEAGFPPGVVNILP
GFGPIVGAAIASHVGIDKIAFTGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNIIFADAD
LDYAVEQAHQGVFFNQGQCCTAGSRIYVEESIYEEFVRRSVERAKRRVVGSPFDPTTEQG
PQIDKKQYNKILELIQSGITEGAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG
PVQEILRFKTVDEVIERANNSDFGLVAAVFTNDINKALTVSSAMQAGTVWINCYNALNAQ
SPFGGFKMSGNGREMGESGLREYSEVKTVTIKIPQKNS
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| BDBM50459608 |
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| n/a |
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| Name | BDBM50459608 |
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| Synonyms: | CHEBI:90441 | CHEMBL3276621 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H20Cl4N2O2 |
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| Mol. Mass. | 366.111 |
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| SMILES | ClC(Cl)C(=O)NCCCCCCCCNC(=O)C(Cl)Cl |
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| Structure | 
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