| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial pyruvate carrier 2 |
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| Ligand | BDBM50466687 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1793755 (CHEMBL4265674) |
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| IC50 | 1200±n/a nM |
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| Citation |  Tanis, SP; Colca, JR; Parker, TT; Artman, GD; Larsen, SD; McDonald, WG; Gadwood, RC; Kletzien, RF; Zeller, JB; Lee, PH; Adams, WJ PPAR?-sparing thiazolidinediones as insulin sensitizers. Design, synthesis and selection of compounds for clinical development. Bioorg Med Chem26:5870-5884 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitochondrial pyruvate carrier 2 |
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| Name: | Mitochondrial pyruvate carrier 2 |
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| Synonyms: | BRP44 | Brain protein 44 | MPC2 | MPC2_HUMAN | Mitochondrial pyruvate carrier 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 14291.32 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_117931 |
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| Residue: | 127 |
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| Sequence: | MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADM
ARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQE
LKAKAHK
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| BDBM50466687 |
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| n/a |
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| Name | BDBM50466687 |
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| Synonyms: | CHEMBL4291468 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H17NO5S |
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| Mol. Mass. | 371.407 |
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| SMILES | COc1cccc(c1)C(=O)COc1ccc(CC2SC(=O)NC2=O)cc1 |
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| Structure | 
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