Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50466974 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1794680 (CHEMBL4266797) |
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Ki | 17±n/a nM |
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Citation | Zampieri, D; Romano, M; Menegazzi, R; Mamolo, MG New piperidine-based derivatives as sigma receptor ligands. Synthesis and pharmacological evaluation. Bioorg Med Chem Lett28:3206-3209 (2018) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25266.54 |
Organism: | RAT |
Description: | Q9R0C9 |
Residue: | 223 |
Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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BDBM50466974 |
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n/a |
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Name | BDBM50466974 |
Synonyms: | CHEMBL4285413 |
Type | Small organic molecule |
Emp. Form. | C20H32N2O |
Mol. Mass. | 316.4809 |
SMILES | CCCCCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O |
Structure |
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