| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50467330 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1795806 (CHEMBL4267923) |
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| IC50 | 36±n/a nM |
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| Citation |  Gu, SX; Lu, HH; Liu, GY; Ju, XL; Zhu, YY Advances in diarylpyrimidines and related analogues as HIV-1 nonnucleoside reverse transcriptase inhibitors. Eur J Med Chem158:371-392 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50467330 |
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| n/a |
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| Name | BDBM50467330 |
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| Synonyms: | CHEMBL307950 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21N5 |
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| Mol. Mass. | 355.4356 |
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| SMILES | Cc1cc(C)c(Nc2nc(Nc3ccc(cc3)C#N)ncc2C=C)c(C)c1 |
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| Structure | 
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