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TargetFatty acid-binding protein 5
LigandBDBM50468436
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1799515 (CHEMBL4271807)
Ki 850±n/a nM
Citation Yan, SElmes, MWTong, SHu, KAwwa, MTeng, GYHJing, YFreitag, MGan, QClement, TWei, LSweeney, JMJoseph, OMChe, JCarbonetti, GSWang, LBogdan, DMFalcone, JSmietalo, NZhou, YRalph, BHsu, HCLi, HRizzo, RCDeutsch, DGKaczocha, MOjima, I SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. Eur J Med Chem154:233-252 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Fatty acid-binding protein 5
Name:Fatty acid-binding protein 5
Synonyms:FABP5 | FABP5_HUMAN | Fatty acid binding protein epidermal | Fatty acid-binding protein 5 (FABP5)
Type:Enzyme
Mol. Mass.:15164.79
Organism:Homo sapiens (Human)
Description:Q01469
Residue:135
Sequence:
MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
VMNNVTCTRIYEKVE
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  Blast E-value cutoff:
BDBM50468436
n/a
NameBDBM50468436
Synonyms:CHEMBL4295043 | US10968163, Compound 3h
TypeSmall organic molecule
Emp. Form.C30H24O4
Mol. Mass.448.5092
SMILESOC(=O)[C@H]1[C@@H]([C@@H]([C@H]1c1ccccc1)C(=O)Oc1cccc(c1)-c1ccccc1)c1ccccc1 |r,wU:4.31,5.14,wD:3.2,6.7,(29.04,-31.59,;27.56,-31.19,;27.16,-29.7,;26.47,-32.28,;24.93,-32.28,;24.93,-33.82,;26.47,-33.82,;27.56,-34.91,;27.15,-36.39,;28.24,-37.48,;29.73,-37.08,;30.12,-35.59,;29.03,-34.51,;23.84,-34.91,;22.35,-34.51,;24.24,-36.39,;23.15,-37.48,;23.55,-38.96,;22.47,-40.05,;20.97,-39.65,;20.57,-38.16,;21.66,-37.08,;19.09,-37.77,;18.7,-36.28,;17.21,-35.88,;16.12,-36.97,;16.52,-38.46,;18.01,-38.86,;23.84,-31.19,;24.24,-29.71,;23.15,-28.62,;21.66,-29.02,;21.27,-30.51,;22.36,-31.6,)|
Structure
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