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TargetFatty acid-binding protein, brain
LigandBDBM50468471
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1799516 (CHEMBL4271808)
Ki 890±n/a nM
Citation Yan, SElmes, MWTong, SHu, KAwwa, MTeng, GYHJing, YFreitag, MGan, QClement, TWei, LSweeney, JMJoseph, OMChe, JCarbonetti, GSWang, LBogdan, DMFalcone, JSmietalo, NZhou, YRalph, BHsu, HCLi, HRizzo, RCDeutsch, DGKaczocha, MOjima, I SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. Eur J Med Chem154:233-252 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Fatty acid-binding protein, brain
Name:Fatty acid-binding protein, brain
Synonyms:B-FABP | BLBP | FABP7 | FABP7_HUMAN | FABPB | MRG
Type:PROTEIN
Mol. Mass.:14886.73
Organism:Homo sapiens
Description:ChEMBL_116822
Residue:132
Sequence:
MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN
TEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTLTF
GDVVAVRHYEKA
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  Blast E-value cutoff:
BDBM50468471
n/a
NameBDBM50468471
Synonyms:CHEMBL4289745
TypeSmall organic molecule
Emp. Form.C28H22O4
Mol. Mass.422.4719
SMILESOC(=O)[C@H]1[C@H]([C@@H]([C@@H]1c1ccccc1)C(=O)Oc1cccc2ccccc12)c1ccccc1 |r,wU:3.2,4.29,wD:6.7,5.14,(72.23,-4.49,;70.74,-4.09,;70.35,-2.6,;69.65,-5.18,;69.65,-6.72,;68.11,-6.72,;68.11,-5.18,;67.03,-4.09,;67.43,-2.61,;66.34,-1.52,;64.85,-1.92,;64.46,-3.42,;65.55,-4.5,;67.03,-7.81,;67.42,-9.3,;65.54,-7.41,;64.45,-8.5,;62.97,-8.1,;61.88,-9.19,;62.28,-10.68,;63.78,-11.07,;64.18,-12.54,;65.65,-12.93,;66.73,-11.84,;66.33,-10.37,;64.85,-9.98,;70.74,-7.81,;70.34,-9.3,;71.43,-10.39,;72.92,-9.99,;73.31,-8.49,;72.22,-7.41,)|
Structure
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