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TargetFatty acid-binding protein 5
LigandBDBM50468433
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1799515 (CHEMBL4271807)
Ki 790±n/a nM
Citation Yan, SElmes, MWTong, SHu, KAwwa, MTeng, GYHJing, YFreitag, MGan, QClement, TWei, LSweeney, JMJoseph, OMChe, JCarbonetti, GSWang, LBogdan, DMFalcone, JSmietalo, NZhou, YRalph, BHsu, HCLi, HRizzo, RCDeutsch, DGKaczocha, MOjima, I SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. Eur J Med Chem154:233-252 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Fatty acid-binding protein 5
Name:Fatty acid-binding protein 5
Synonyms:FABP5 | FABP5_HUMAN | Fatty acid binding protein epidermal | Fatty acid-binding protein 5 (FABP5)
Type:Enzyme
Mol. Mass.:15164.79
Organism:Homo sapiens (Human)
Description:Q01469
Residue:135
Sequence:
MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
VMNNVTCTRIYEKVE
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  Blast E-value cutoff:
BDBM50468433
n/a
NameBDBM50468433
Synonyms:CHEMBL4281879 | US20230365488, Compound 1x
TypeSmall organic molecule
Emp. Form.C28H22O4
Mol. Mass.422.4719
SMILESOC(=O)[C@H]1[C@@H]([C@@H]([C@H]1c1ccccc1)C(=O)Oc1cccc2ccccc12)c1ccccc1 |r,wU:4.29,5.14,wD:3.2,6.7,(86.26,-4.37,;84.78,-3.97,;84.38,-2.49,;83.69,-5.06,;82.15,-5.06,;82.15,-6.6,;83.69,-6.6,;84.78,-7.69,;84.37,-9.18,;85.46,-10.27,;86.95,-9.87,;87.34,-8.37,;86.25,-7.29,;81.06,-7.69,;81.46,-9.18,;79.57,-7.29,;78.48,-8.38,;77,-7.98,;75.91,-9.07,;76.31,-10.56,;77.81,-10.95,;78.21,-12.42,;79.69,-12.81,;80.76,-11.72,;80.36,-10.25,;78.89,-9.87,;81.06,-3.97,;81.46,-2.49,;80.37,-1.41,;78.88,-1.8,;78.49,-3.3,;79.58,-4.38,)|
Structure
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