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TargetAlpha-1A adrenergic receptor
LigandBDBM50029051
Substrate/Competitorn/a
Meas. Tech.ChEMBL_34166 (CHEMBL858093)
EC50 1175±n/a nM
Citation Meyer, MD; Altenbach, RJ; Hancock, AA; Buckner, SA; Knepper, SM; Kerwin, JF Synthesis and in vitro characterization of N-[5-(4,5-dihydro-1H-imidazol-2-yl)-2-hydroxy-5,6,7,8- tetrahydronaphthalen-1-yl]methanesulfonamide and its enantiomers: a novel selective alpha 1A receptor agonist. J Med Chem39:4116-9 (1996) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-1A adrenergic receptor
Name:Alpha-1A adrenergic receptor
Synonyms:ADA1A_RAT | Adra1a | Adra1c | Alpha-1 adrenoreceptor | Alpha-1A adrenoceptor | Alpha-1A adrenoreceptor | Alpha-1C adrenergic receptor | adrenergic Alpha1A
Type:Protein
Mol. Mass.:51620.15
Organism:Rattus norvegicus (Rat)
Description:P43140
Residue:466
Sequence:
MVLLSENASEGSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSV
THYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCII
SIDRYIGVSYPLRYPTIVTQRRGVRALLCVWVLSLVISIGPLFGWRQPAPEDETICQINE
EPGYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN
VPAEGGGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPD
FKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRRQSSKHALGYTL
HPPSQALEGQHRDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPQGSARITVPKDQSACT
TARVRSKSFLQVCCCVGSSAPRPEENHQVPTIKIHTISLGENGEEV
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BDBM50029051
n/a
NameBDBM50029051
Synonyms:(-)-arterenol | (-)-noradrenaline | (-)-norepinephrine | (R)-(-)-norepinephrine | (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol | (R)-noradrenaline | (R)-norepinephrine | 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | CHEMBL1437 | NOREPINEPHRINE
TypeSmall organic molecule
Emp. Form.C8H11NO3
Mol. Mass.169.1778
SMILESNC[C@H](O)c1ccc(O)c(O)c1 |r|
Structure
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