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TargetSimilar to alpha-tubulin isoform 1
LigandBDBM50216333
Substrate/Competitorn/a
Meas. Tech.ChEMBL_211324 (CHEMBL818983)
IC50 2200±n/a nM
Citation Poncet, JBusquet, MRoux, FPierré, AAtassi, GJouin, P Synthesis and biological activity of chimeric structures derived from the cytotoxic natural compounds dolastatin 10 and dolastatin 15. J Med Chem41:1524-30 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Similar to alpha-tubulin isoform 1
Name:Similar to alpha-tubulin isoform 1
Synonyms:Similar to alpha-tubulin isoform 1
Type:PROTEIN
Mol. Mass.:10383.05
Organism:Bos taurus
Description:ChEMBL_104716
Residue:99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50216333
n/a
NameBDBM50216333
Synonyms:CHEBI:67357 | DOLASTATIN-10 | Dolastatin 10 | Dolostatin 10
TypeSmall organic molecule
Emp. Form.C42H68N6O6S
Mol. Mass.785.091
SMILES[H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1 |r|
Structure
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