| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histamine H3 receptor |
|---|
| Ligand | BDBM50222968 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_86930 (CHEMBL697539) |
|---|
| Ki | 0.125893±n/a nM |
|---|
| Citation |  Kovalainen, JT; Christiaans, JA; Kotisaari, S; Laitinen, JT; Männistö, PT; Tuomisto, L; Gynther, J Synthesis and in vitro pharmacology of a series of new chiral histamine H3-receptor ligands: 2-(R and S)-Amino-3-(1H-imidazol-4(5)-yl)propyl ether derivatives. J Med Chem42:1193-202 (1999) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histamine H3 receptor |
|---|
| Name: | Histamine H3 receptor |
|---|
| Synonyms: | HH3R | HRH3_RAT | Hrh3 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 48607.98 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | n/a |
|---|
| Residue: | 445 |
|---|
| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAA
ASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSL
AIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFR
RAFTKLLCPQKLKVQPHGSLEQCWK
|
|
|
|---|
| BDBM50222968 |
|---|
| n/a |
|---|
| Name | BDBM50222968 |
|---|
| Synonyms: | Cipralisant | GT-2331 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H20N2 |
|---|
| Mol. Mass. | 216.322 |
|---|
| SMILES | CC(C)(C)CCC#C[C@@H]1C[C@H]1c1c[nH]cn1 |
|---|
| Structure | 
|
|---|
Search and Browse
