Reaction Details | |||
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Target | DNA polymerase beta | ||
Ligand | BDBM50027110 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEBML_50773 | ||
IC50 | 104000±n/a nM | ||
Citation | Wu, RS; Wolpert-DeFilippes, MK; Quinn, FR Quantitative structure--activity correlations of rifamycins as inhibitors of viral RNA-directed DNA polymerase and mammalian alpha and beta DNA polymerases. J Med Chem23:256-61 (1980) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
DNA polymerase beta | |||
Name: | DNA polymerase beta | ||
Synonyms: | DPOLB_MOUSE | Polb | ||
Type: | PROTEIN | ||
Mol. Mass.: | 38297.87 | ||
Organism: | Mus musculus | ||
Description: | ChEMBL_50773 | ||
Residue: | 335 | ||
Sequence: |
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BDBM50027110 | |||
n/a | |||
Name | BDBM50027110 | ||
Synonyms: | 26-formyl-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate | CHEMBL87160 | ||
Type | Small organic molecule | ||
Emp. Form. | C38H47NO12 | ||
Mol. Mass. | 709.7793 | ||
SMILES | COC1\C=C\OC2(C)Oc3c(C2=O)c2cc(C=O)c(NC(=O)\C(C)=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)c(O)c2c(O)c3C |c:24,t:3,26| | ||
Structure |