Reaction Details | |||
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Target | Gag-Pol polyprotein | ||
Ligand | BDBM50027121 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_196794 (CHEMBL799737) | ||
Ki | 107151931±n/a nM | ||
Citation | Wu, RS; Wolpert-DeFilippes, MK; Quinn, FR Quantitative structure--activity correlations of rifamycins as inhibitors of viral RNA-directed DNA polymerase and mammalian alpha and beta DNA polymerases. J Med Chem23:256-61 (1980) [PubMed] | ||
More Info.: | Get all data from this article, Assay Method | ||
Gag-Pol polyprotein | |||
Name: | Gag-Pol polyprotein | ||
Synonyms: | POL_WMSV | Simian sarcoma virus Pol protein | pol | ||
Type: | PROTEIN | ||
Mol. Mass.: | 32733.90 | ||
Organism: | Woolly monkey sarcoma virus | ||
Description: | ChEMBL_196792 | ||
Residue: | 294 | ||
Sequence: |
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BDBM50027121 | |||
n/a | |||
Name | BDBM50027121 | ||
Synonyms: | 2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-N'-Methylene-N,N-dioctyl-hydrazine-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate | 2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-N,N-Dioctyl-N'-methylene-hydrazine-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate | CHEMBL84625 | ||
Type | Small organic molecule | ||
Emp. Form. | C54H81N3O11 | ||
Mol. Mass. | 948.2344 | ||
SMILES | CCCCCCCCN(CCCCCCCC)\N=C\c1cc2c3C(=O)C4(C)Oc3c(C)c(O)c2c(O)c1NC(=O)\C(C)=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C(C)C(OC)\C=C\O4 |c:44,t:46,68| | ||
Structure |