| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M2 |
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| Ligand | BDBM50474565 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_140026 (CHEMBL745569) |
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| EC50 | 740±n/a nM |
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| Citation |  Stiefl, N; Baumann, K Mapping property distributions of molecular surfaces: algorithm and evaluation of a novel 3D quantitative structure-activity relationship technique. J Med Chem46:1390-407 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M2 |
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| Name: | Muscarinic acetylcholine receptor M2 |
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| Synonyms: | ACM2_PIG | CHRM2 | Cholinergic, muscarinic | GPM2 | LOC100715343 | Muscarinic acetylcholine receptor M2 | Muscarinic receptor 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51688.65 |
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| Organism: | GUINEA PIG |
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| Description: | Cholinergic, muscarinic 0 GUINEA PIG::P06199 |
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| Residue: | 466 |
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| Sequence: | MNNSTNSSNSGLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQEPVSPSLVQGRI
VKPNNNNMPGSDEALEHNKIQNGKAPRDAVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIKIVTKTQKSDSCTPANTTVELVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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| BDBM50474565 |
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| n/a |
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| Name | BDBM50474565 |
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| Synonyms: | CHEMBL609124 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H40N6O4 |
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| Mol. Mass. | 596.7192 |
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| SMILES | O=C1N(CCCN(CCCCCCN(CCCN2C(=O)c3ccccc3C2=O)CCC#N)CCC#N)C(=O)c2ccccc12 |
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| Structure | 
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