| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 5A |
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| Ligand | BDBM50474947 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304047 (CHEMBL840224) |
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| Ki | 32±n/a nM |
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| Citation |  Corbett, DF; Heightman, TD; Moss, SF; Bromidge, SM; Coggon, SA; Longley, MJ; Roa, AM; Williams, JA; Thomas, DR Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry. Bioorg Med Chem Lett15:4014-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 5A |
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| Name: | 5-hydroxytryptamine receptor 5A |
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| Synonyms: | 5-HT-5 | 5-HT-5A | 5-hydroxytryptamine receptor 5 (5-HT5) | 5-hydroxytryptamine receptor 5A (5-HT5A) | 5HT5A_HUMAN | HTR5A | Serotonin (5-HT) receptor | Serotonin receptor 5A |
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| Type: | Enzyme |
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| Mol. Mass.: | 40266.25 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47898 |
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| Residue: | 357 |
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| Sequence: | MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLL
VLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIAC
DVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFG
WGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVS
PISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIP
FFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
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| BDBM50474947 |
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| n/a |
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| Name | BDBM50474947 |
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| Synonyms: | CHEMBL186849 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H45F3N4O3 |
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| Mol. Mass. | 626.752 |
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| SMILES | OC(=O)C(F)(F)F.CN(C)CCN(Cc1ccc(cc1)-c1ccc(CNCCc2ccccn2)cc1)C(=O)CCC1CCCC1 |
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| Structure | 
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