| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 1 |
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| Ligand | BDBM50120392 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2263480 |
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| Ki | 21±n/a nM |
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| Citation |  Ronchetti, R; Moroni, G; Carotti, A; Gioiello, A; Camaioni, E Recent advances in urea- and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis. RSC Med Chem12:1046-1064 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 1 |
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| Name: | Neuropeptide Y receptor type 1 |
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| Synonyms: | NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44399.07 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y1 NPY1R HUMAN::P25929 |
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| Residue: | 384 |
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| Sequence: | MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLA
LIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQ
CVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMT
DEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKR
RNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNL
LFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVS
KTSLKQASPVAFKKINNNDDNEKI
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| BDBM50120392 |
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| n/a |
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| Name | BDBM50120392 |
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| Synonyms: | CHEMBL5282574 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H40N4O7 |
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| Mol. Mass. | 628.7147 |
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| SMILES | COC(=O)C1=CNC(C)=C(C1c1cccc(Nc2c(NCCCN3CCC(CC3)c3cccc(OC)c3)c(=O)c2=O)c1)C(=O)OC |c:8,t:4| |
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| Structure | 
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