| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM50297894 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_340154 (CHEMBL865589) |
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| Ki | 65±n/a nM |
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| Citation |  Raubo, P; Beer, MS; Hunt, PA; Huscroft, IT; London, C; Stanton, JA; Kulagowski, JJ Aminoalkyl phenyl sulfones--a novel series of 5-HT7 receptor ligands. Bioorg Med Chem Lett16:1255-8 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A |
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| Type: | undefined |
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| Mol. Mass.: | 52607.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28223 |
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| Residue: | 471 |
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| Sequence: | MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGC
LSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYK
SSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
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| BDBM50297894 |
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| n/a |
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| Name | BDBM50297894 |
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| Synonyms: | 2-(3-(1-(phenylsulfonyl)cyclobutyl)propyl)-1,2,3,4-tetrahydroisoquinoline | CHEMBL204171 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27NO2S |
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| Mol. Mass. | 369.52 |
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| SMILES | O=S(=O)(c1ccccc1)C1(CCCN2CCc3ccccc3C2)CCC1 |
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| Structure | 
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