| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cholesterol side-chain cleavage enzyme, mitochondrial |
|---|
| Ligand | BDBM50476077 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_424409 (CHEMBL910687) |
|---|
| IC50 | 29600±n/a nM |
|---|
| Citation |  Tandon, VK; Maurya, HK; Yadav, DB; Tripathi, A; Kumar, M; Shukla, PK Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents. Bioorg Med Chem Lett16:5883-7 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cholesterol side-chain cleavage enzyme, mitochondrial |
|---|
| Name: | Cholesterol side-chain cleavage enzyme, mitochondrial |
|---|
| Synonyms: | CP11A_RAT | Cyp11a | Cyp11a-1 | Cyp11a1 | Cytochrome P450 11A1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 60603.33 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_50353 |
|---|
| Residue: | 526 |
|---|
| Sequence: | MLAKGLCLRSVLVKSCQPFLSPVWQGPGLATGNGAGISSTNSPRSFNEIPSPGDNGWINL
YHFLRENGTHRIHYHHMQNFQKYGPIYREKLGNMESVYILDPKDAATLFSCEGPNPERYL
VPPWVAYHQYYQRPIGVLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVL
HRRIKQQNSGKFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFIDAVYQMFH
TSVPMLNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQKRDFSKYPGVLY
SLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWNLYEMAHNLKVQEMLRAEVLAARRQA
QGDMAKMVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLRNYKIPAKTLVQVASYAMG
RESSFFPNPNKFDPTRWLEKSQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENF
RIEVQSIRDVGTKFNLILMPEKPIFFNFQPLKQDLGSTMPRKGDTV
|
|
|
|---|
| BDBM50476077 |
|---|
| n/a |
|---|
| Name | BDBM50476077 |
|---|
| Synonyms: | CHEMBL386004 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H11ClO4S |
|---|
| Mol. Mass. | 310.753 |
|---|
| SMILES | CCOC(=O)CSC1=C(Cl)C(=O)c2ccccc2C1=O |c:7| |
|---|
| Structure | 
|
|---|
Search and Browse
