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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cathepsin K | ||
| Ligand | BDBM50323204 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_425100 (CHEMBL913665) | ||
| IC50 | 1570±n/a nM | ||
| Citation |  Zeng, GZ; Tan, NH; Hao, XJ; Mu, QZ; Li, RT Natural inhibitors targeting osteoclast-mediated bone resorption. Bioorg Med Chem Lett16:6178-80 (2006) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cathepsin K | |||
| Name: | Cathepsin K | ||
| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 36975.68 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P43235 | ||
| Residue: | 329 | ||
| Sequence: |
| ||
| BDBM50323204 | |||
| n/a | |||
| Name | BDBM50323204 | ||
| Synonyms: | 7'',4'''-dimethylamentoflavone | CHEMBL374055 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C32H22O10 | ||
| Mol. Mass. | 566.5111 | ||
| SMILES | COc1ccc(cc1)-c1cc(=O)c2c(O)cc(OC)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 |(6.65,-6.92,;5.32,-7.68,;5.32,-9.22,;6.66,-9.99,;6.66,-11.53,;5.32,-12.3,;3.99,-11.54,;3.99,-10,;5.32,-13.84,;6.66,-14.6,;6.66,-16.14,;7.99,-16.91,;5.33,-16.91,;5.34,-18.45,;6.68,-19.22,;4.01,-19.23,;2.67,-18.46,;1.34,-19.23,;1.34,-20.77,;2.68,-16.92,;1.34,-16.15,;.01,-16.92,;-1.33,-16.15,;-1.33,-14.62,;-.01,-13.84,;1.34,-14.61,;2.67,-13.83,;-2.66,-16.92,;-2.66,-18.48,;-4,-19.26,;-4,-20.8,;-5.34,-18.49,;-5.35,-16.94,;-6.68,-16.17,;-8.01,-16.94,;-9.34,-16.17,;-8.01,-18.49,;-6.68,-19.26,;-6.68,-20.8,;-4.01,-16.15,;4,-16.15,;3.98,-14.61,)| | ||
| Structure | 
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