| Reaction Details |
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 | Report a problem with these data |
| Target | HIV-1 protease |
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| Ligand | BDBM50476647 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_445722 (CHEMBL896013) |
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| Ki | 2.1±n/a nM |
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| Citation |  Wang, YF; Tie, Y; Boross, PI; Tozser, J; Ghosh, AK; Harrison, RW; Weber, IT Potent new antiviral compound shows similar inhibition and structural interactions with drug resistant mutants and wild type HIV-1 protease. J Med Chem50:4509-15 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| HIV-1 protease |
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| Name: | HIV-1 protease |
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| Synonyms: | HIV-1 | HIV-1 protease | protease |
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| Type: | PROTEIN |
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| Mol. Mass.: | 10795.19 |
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| Organism: | Human immunodeficiency virus |
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| Description: | ChEMBL_118439 |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF
|
|
|
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| BDBM50476647 |
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| n/a |
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| Name | BDBM50476647 |
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| Synonyms: | CHEMBL178593 | GRL-98065 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H36N2O9S |
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| Mol. Mass. | 576.658 |
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| SMILES | [H][C@@]12CCO[C@]1([H])OC[C@@H]2OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc2OCOc2c1 |r| |
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| Structure | 
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