Reaction Details |
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Target | Reverse transcriptase protein |
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Ligand | BDBM50478031 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_465974 (CHEMBL947217) |
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IC50 | 72±n/a nM |
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Citation | San Juan, AA 3D-QSAR models on clinically relevant K103N mutant HIV-1 reverse transcriptase obtained from two strategic considerations. Bioorg Med Chem Lett18:1181-94 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Reverse transcriptase protein |
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Name: | Reverse transcriptase protein |
Synonyms: | Reverse Transcriptase | Reverse Transcriptase (A62V) | Reverse Transcriptase (F61A) |
Type: | Protein |
Mol. Mass.: | 30203.56 |
Organism: | Human immunodeficiency virus 1 |
Description: | Q9WJQ2 |
Residue: | 259 |
Sequence: | PISPIEPVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYEHHPDKWT
VQPIVLPEKDSWTVNDIQK
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BDBM50478031 |
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n/a |
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Name | BDBM50478031 |
Synonyms: | CHEMBL201372 |
Type | Small organic molecule |
Emp. Form. | C21H15ClF2N2O4 |
Mol. Mass. | 432.805 |
SMILES | COc1ccc(NC(=O)COc2ccc(Cl)cc2C(=O)c2cc(F)cc(F)c2)cn1 |
Structure |
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