| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50029196 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_519245 (CHEMBL946684) |
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| IC50 | >100000±n/a nM |
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| Citation |  Xia, CN; Li, HB; Liu, F; Hu, WX Synthesis of trans-caffeate analogues and their bioactivities against HIV-1 integrase and cancer cell lines. Bioorg Med Chem Lett18:6553-7 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | pol |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32203.43 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_106649 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
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| BDBM50029196 |
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| n/a |
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| Name | BDBM50029196 |
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| Synonyms: | (E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid ethyl ester | (E)-ethyl 3-(3,4-dihydroxyphenyl)acrylate | 3-(3,4-Dihydroxy-phenyl)-acrylic acid ethyl ester | CHEMBL17347 | Ethyl 1-(3',4'-dihydroxyphenyl)propenate | Ethyl caffeate | ethyl 3-(3,4-dihydroxyphenyl)acrylate |
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| Type | Small organic molecule |
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| Emp. Form. | C11H12O4 |
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| Mol. Mass. | 208.2106 |
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| SMILES | CCOC(=O)\C=C\c1ccc(O)c(O)c1 |
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| Structure | 
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