Reaction Details |
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Target | Integrase |
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Ligand | BDBM50276913 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_519245 (CHEMBL946684) |
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IC50 | >100000±n/a nM |
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Citation | Xia, CN; Li, HB; Liu, F; Hu, WX Synthesis of trans-caffeate analogues and their bioactivities against HIV-1 integrase and cancer cell lines. Bioorg Med Chem Lett18:6553-7 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Integrase |
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Name: | Integrase |
Synonyms: | pol |
Type: | PROTEIN |
Mol. Mass.: | 32203.43 |
Organism: | Human immunodeficiency virus 1 |
Description: | ChEMBL_106649 |
Residue: | 288 |
Sequence: | FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
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BDBM50276913 |
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n/a |
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Name | BDBM50276913 |
Synonyms: | CHEMBL17362 | Propyl 3-(3,4-Dihydroxyphenyl)Acrylate |
Type | Small organic molecule |
Emp. Form. | C12H14O4 |
Mol. Mass. | 222.2372 |
SMILES | CCCOC(=O)\C=C\c1ccc(O)c(O)c1 |
Structure |
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