Reaction Details |
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Target | Reverse transcriptase |
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Ligand | BDBM50480361 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_501126 (CHEMBL978904) |
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IC50 | 15260±n/a nM |
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Citation | Galal, SA; Abd El-All, AS; Abdallah, MM; El-Diwani, HI Synthesis of potent antitumor and antiviral benzofuran derivatives. Bioorg Med Chem Lett19:2420-8 (2009) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Reverse transcriptase |
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Name: | Reverse transcriptase |
Synonyms: | n/a |
Type: | Protein |
Mol. Mass.: | 29598.37 |
Organism: | Human immunodeficiency virus 1 |
Description: | Q9WKE8 |
Residue: | 254 |
Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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BDBM50480361 |
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n/a |
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Name | BDBM50480361 |
Synonyms: | CHEMBL511905 |
Type | Small organic molecule |
Emp. Form. | C17H14N2O5S |
Mol. Mass. | 358.368 |
SMILES | COc1c(O)c(C(=O)C2=CN3C=CSC3N=C2)c(OC)c2ccoc12 |c:11,16,t:8| |
Structure |
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