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TargetReverse transcriptase
LigandBDBM50480361
Substrate/Competitorn/a
Meas. Tech.ChEMBL_501126 (CHEMBL978904)
IC50 15260±n/a nM
Citation Galal, SAAbd El-All, ASAbdallah, MMEl-Diwani, HI Synthesis of potent antitumor and antiviral benzofuran derivatives. Bioorg Med Chem Lett19:2420-8 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Reverse transcriptase
Name:Reverse transcriptase
Synonyms:n/a
Type:Protein
Mol. Mass.:29598.37
Organism:Human immunodeficiency virus 1
Description:Q9WKE8
Residue:254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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  Blast E-value cutoff:
BDBM50480361
n/a
NameBDBM50480361
Synonyms:CHEMBL511905
TypeSmall organic molecule
Emp. Form.C17H14N2O5S
Mol. Mass.358.368
SMILESCOc1c(O)c(C(=O)C2=CN3C=CSC3N=C2)c(OC)c2ccoc12 |c:11,16,t:8|
Structure
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