| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50482339 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_642255 (CHEMBL1177074) |
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| IC50 | 61±n/a nM |
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| Citation |  Younis, Y; Hunter, R; Muhanji, CI; Hale, I; Singh, R; Bailey, CM; Sullivan, TJ; Anderson, KS [d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase. Bioorg Med Chem18:4661-73 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50482339 |
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| n/a |
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| Name | BDBM50482339 |
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| Synonyms: | CHEMBL1173828 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H28BrN5O6S |
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| Mol. Mass. | 642.521 |
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| SMILES | COc1ccc(OCCC#Cc2cn([C@@H]3O[C@H](CO)C=C3)c(=O)[nH]c2=O)c(CCNC(=S)Nc2ccc(Br)cn2)c1 |r,c:19| |
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| Structure | 
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