| Reaction Details |
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 | Report a problem with these data |
| Target | Protease |
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| Ligand | BDBM50483111 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_685646 (CHEMBL1285548) |
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| Ki | 0.020000±n/a nM |
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| Citation |  Ali, A; Reddy, GS; Nalam, MN; Anjum, SG; Cao, H; Schiffer, CA; Rana, TM Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones. J Med Chem53:7699-708 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protease |
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| Name: | Protease |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 10904.79 |
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| Organism: | Human immunodeficiency virus 1 (HIV-1) |
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| Description: | Q9YQ12 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50483111 |
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| n/a |
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| Name | BDBM50483111 |
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| Synonyms: | CHEMBL1276091 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H38N4O7S |
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| Mol. Mass. | 610.721 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)N(CC(C)C)C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(C(=O)O1)c1cccc(N)c1 |r| |
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| Structure | 
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