| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Penicillin-binding protein 2x |
|---|
| Ligand | BDBM50422689 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_706024 (CHEMBL1662838) |
|---|
| IC50 | 0.094±n/a nM |
|---|
| Citation |  Kosowska-Shick, K; McGhee, P; Appelbaum, PC Binding of faropenem and other beta-lactam agents to penicillin-binding proteins of pneumococci with various beta-lactam susceptibilities. Antimicrob Agents Chemother53:2176-80 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Penicillin-binding protein 2x |
|---|
| Name: | Penicillin-binding protein 2x |
|---|
| Synonyms: | PBPX_STRPN | pbpX |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 82307.00 |
|---|
| Organism: | Streptococcus pneumoniae |
|---|
| Description: | ChEMBL_653273 |
|---|
| Residue: | 750 |
|---|
| Sequence: | MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNFAVIIGTGTRFGTDLAK
EAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDENYKSATGKILYVEKTQFN
KVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITYANMMSIKKELEAAEVKGIDF
TTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSGMESSLNSILAGTDGIITYEKDR
LGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQMDAFQEKVKGKYMTATLVSAKTGE
ILATTQRPTFDADTKEGITEDFVWRDILYQSNYEPGSTMKVMMLAAAIDNNTFPGGEVFN
SSELKIADATIRDWDVNEGLTGGRTMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFK
FGVPTRFGLTDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKFI
SAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVP
GQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQL
GEFANPILERASAMKDSLNLQTTAKALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQP
IVVGTGTKIKNSSAEEGKNLAPNQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEF
QGSGSTVQKQDVRANTAIKDIKKITLTLGD
|
|
|
|---|
| BDBM50422689 |
|---|
| n/a |
|---|
| Name | BDBM50422689 |
|---|
| Synonyms: | 640/359 | CEFUROXIME |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H16N4O8S |
|---|
| Mol. Mass. | 424.385 |
|---|
| SMILES | CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(O)=O)c1ccco1 |r,c:16| |
|---|
| Structure | 
|
|---|
Search and Browse
