| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50483358 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_717540 (CHEMBL1671032) |
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| IC50 | 251±n/a nM |
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| Citation |  De Luca, L; De Grazia, S; Ferro, S; Gitto, R; Christ, F; Debyser, Z; Chimirri, A HIV-1 integrase strand-transfer inhibitors: design, synthesis and molecular modeling investigation. Eur J Med Chem46:756-64 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | pol |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32203.43 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_106649 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
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| BDBM50483358 |
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| n/a |
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| Name | BDBM50483358 |
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| Synonyms: | CHEMBL1669249 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18FNO6 |
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| Mol. Mass. | 399.3691 |
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| SMILES | COc1cc(OC)c2n(Cc3ccc(F)cc3)cc(C(=O)\C=C(/O)C(O)=O)c2c1 |
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| Structure | 
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