| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50418089 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_734864 (CHEMBL1693126) |
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| IC50 | 8.99±n/a nM |
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| Citation |  Balestrieri, E; Pizzimenti, F; Ferlazzo, A; Giofrč, SV; Iannazzo, D; Piperno, A; Romeo, R; Chiacchio, MA; Mastino, A; Macchi, B Antiviral activity of seed extract from Citrus bergamia towards human retroviruses. Bioorg Med Chem19:2084-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50418089 |
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| n/a |
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| Name | BDBM50418089 |
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| Synonyms: | Limonin |
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| Type | Small organic molecule |
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| Emp. Form. | C26H30O8 |
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| Mol. Mass. | 470.5116 |
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| SMILES | [H][C@]12O[C@@]11[C@@](C)(CC[C@]3([H])[C@@]45COC(=O)C[C@]4([H])OC(C)(C)[C@]5([H])CC(=O)[C@@]13C)[C@@H](OC2=O)c1ccoc1 |r| |
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| Structure | 
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