Reaction Details |
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Target | Protease |
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Ligand | BDBM50483622 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_741066 (CHEMBL1764294) |
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IC50 | 500±n/a nM |
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Citation | Makatini, MM; Petzold, K; Sriharsha, SN; Soliman, ME; Honarparvar, B; Arvidsson, PI; Sayed, Y; Govender, P; Maguire, GE; Kruger, HG; Govender, T Pentacycloundecane-based inhibitors of wild-type C-South African HIV-protease. Bioorg Med Chem Lett21:2274-7 (2011) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Protease |
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Name: | Protease |
Synonyms: | n/a |
Type: | Enzyme |
Mol. Mass.: | 10904.79 |
Organism: | Human immunodeficiency virus 1 (HIV-1) |
Description: | Q9YQ12 |
Residue: | 99 |
Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50483622 |
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n/a |
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Name | BDBM50483622 |
Synonyms: | CHEMBL1761681 |
Type | Small organic molecule |
Emp. Form. | C24H35N5O6 |
Mol. Mass. | 489.5646 |
SMILES | CC[C@H](C)[C@H](NC(=O)[C@@H](N)CO)C(=O)N[C@@H](C)C(=O)N[C@]12NC(=O)[C@]3(O)C4C5C(C14)C1CC5C3C21 |r,THB:26:27:34.33:31,29:28:34.33:31| |
Structure |
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