| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50087419 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_749291 (CHEMBL1785226) |
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| IC50 | 708±n/a nM |
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| Citation |  Leonard, JT; Roy, K Exploring molecular shape analysis of styrylquinoline derivatives as HIV-1 integrase inhibitors. Eur J Med Chem43:81-92 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | pol |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32203.43 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_106649 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
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| BDBM50087419 |
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| n/a |
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| Name | BDBM50087419 |
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| Synonyms: | (E)-2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyquinoline-7-carboxylic acid | 2-(3,4-dihydroxy-5-methoxystyryl)-8-hydroxyquinoline-7-carboxylic acid | 2-[2-((E)-3,4-Dihydroxy-5-methoxy-phenyl)-vinyl]-8-hydroxy-quinoline-7-carboxylic acid | 2-[2-(3,4-Dihydroxy-5-methoxy-phenyl)-vinyl]-8-hydroxy-quinoline-7-carboxylic acid | CHEMBL36640 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H15NO6 |
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| Mol. Mass. | 353.3255 |
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| SMILES | COc1cc(\C=C\c2ccc3ccc(C(O)=O)c(O)c3n2)cc(O)c1O |
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| Structure | 
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