| Reaction Details |
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 | Report a problem with these data |
| Target | Metallo-beta-lactamase type 2 |
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| Ligand | BDBM50484376 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_775599 (CHEMBL1913283) |
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| Ki | 29000±n/a nM |
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| Citation |  Mohamed, MS; Hussein, WM; McGeary, RP; Vella, P; Schenk, G; Abd El-Hameed, RH Synthesis and kinetic testing of new inhibitors for a metallo-?-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa. Eur J Med Chem46:6075-82 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Metallo-beta-lactamase type 2 |
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| Name: | Metallo-beta-lactamase type 2 |
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| Synonyms: | B2 metallo-beta-lactamase | BLA-IMP | BLAB_SERMA | Beta-lactamase type II | IMP-1 | Metallo-beta-lactamase type II |
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| Type: | undefined |
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| Mol. Mass.: | 27125.88 |
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| Organism: | Serratia marcescens |
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| Description: | P52699 |
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| Residue: | 246 |
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| Sequence: | MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
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| BDBM50484376 |
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| n/a |
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| Name | BDBM50484376 |
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| Synonyms: | CHEMBL1910739 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H19N5O |
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| Mol. Mass. | 441.4834 |
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| SMILES | [#6]-[#8]-c1ccc(cc1)-n1c2-[#7]=[#6]-[#7]\[#6](=[#6](\C#N)C#N)-c2c(c1-c1ccccc1)-c1ccccc1 |c:11| |
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| Structure | 
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