| Reaction Details |
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 | Report a problem with these data |
| Target | Protease |
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| Ligand | BDBM50485184 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_821528 (CHEMBL2038196) |
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| IC50 | >2000000±n/a nM |
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| Citation |  Pawar, SA; Jabgunde, AM; Govender, P; Maguire, GE; Kruger, HG; Parboosing, R; Soliman, ME; Sayed, Y; Dhavale, DD; Govender, T Synthesis and molecular modelling studies of novel carbapeptide analogs for inhibition of HIV-1 protease. Eur J Med Chem53:13-21 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protease |
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| Name: | Protease |
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| Synonyms: | n/a |
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| Type: | Enzyme |
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| Mol. Mass.: | 10904.79 |
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| Organism: | Human immunodeficiency virus 1 (HIV-1) |
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| Description: | Q9YQ12 |
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| Residue: | 99 |
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| Sequence: | PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50485184 |
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| n/a |
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| Name | BDBM50485184 |
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| Synonyms: | CHEMBL2035873 |
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| Type | Small organic molecule |
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| Emp. Form. | C39H56N4O10 |
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| Mol. Mass. | 740.8827 |
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| SMILES | COC(=O)[C@H](CC(C)C)NC(C)[C@H](Cc1ccccc1)NC(=O)[C@@H]1O[C@H]([C@@H](O)[C@@H]1O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)OC |r| |
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| Structure | 
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