| Reaction Details |
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 | Report a problem with these data |
| Target | Solute carrier organic anion transporter family member 1C1 |
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| Ligand | BDBM50225220 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_838508 (CHEMBL2078136) |
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| Ki | 270±n/a nM |
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| Citation |  Tohyama, K; Kusuhara, H; Sugiyama, Y Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier. Endocrinology145:4384-91 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Solute carrier organic anion transporter family member 1C1 |
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| Name: | Solute carrier organic anion transporter family member 1C1 |
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| Synonyms: | OATP-14 | OATP-F | OATP2 | Oatp1c1 | Oatpf | Organic anion transporter 2 | Organic anion transporter F | Organic anion-transporting polypeptide 14 | SO1C1_MOUSE | Slc21a14 | Slco1c1 | Solute carrier family 21 member 14 | Solute carrier organic anion transporter family member 1C1 | Thyroxine transporter |
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| Type: | PROTEIN |
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| Mol. Mass.: | 78347.58 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_104629 |
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| Residue: | 715 |
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| Sequence: | MDTSSKENAHLFHKNSAQPAGGPSFTVGYPSTEEARPCCGKLKVFLGALSFVYFAKALAE
GYLKSTVTQIERRFEIPSSLVGIIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCLVMG
FGTMLIAVPQFFMEKYSYEKYERYSPSSNVTPSISPCYLESSSPSPSSILGKSQNKISHE
CVGDSSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPI
FGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPK
TLPRSQSRENSGSTSEKSKFIDDPIHYQMAPGDDKMKIMEMAKDFLPSLKTLFRNPVYIL
YLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKF
RLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCN
SRCKCSDSKWEPMCGDNGITYVSACLAGCQSSSRSGKNIIFSNCTCVGFAAPKSGNWSGM
MGRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVR
VLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSVFLS
MAVLFVLKKKYVSKHSSLITTREKIGMSSSIKKETCAARDRGLQPKYWPGKETRL
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| BDBM50225220 |
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| n/a |
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| Name | BDBM50225220 |
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| Synonyms: | CHEMBL559 | D-thyroxine | O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine | dextrothyroxine |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11I4NO4 |
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| Mol. Mass. | 776.87 |
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| SMILES | N[C@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O |
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| Structure | 
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