| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 2 |
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| Ligand | BDBM50257995 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_902174 (CHEMBL3061572) |
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| IC50 | 1.5±n/a nM |
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| Citation |  TBA Med Chem Res21:100-115 (2012) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 2 |
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| Name: | C-C chemokine receptor type 2 |
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| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41932.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41597 |
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| Residue: | 374 |
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| Sequence: | MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN
MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY
HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK
CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR
AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI
NPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSI
GRAPEASLQDKEGA
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| BDBM50257995 |
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| n/a |
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| Name | BDBM50257995 |
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| Synonyms: | (1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-ethyl tetrahydro-2H-pyran-4-ylamino)-1-isopropylcyclopentanecarboxamide | (1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-ethyltetra hydro-2H-pyran-4-ylamino)-1-isopropylcyclopentanecarboxamide | (1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-ethyltetrahydro-2H-pyran-4-ylamino)-1-isopropylcyclopentane carboxamide | (1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(3-ethyltetrahydro-2H-pyran-4-ylamino)-1-isopropylcyclopentanecarboxamide | CHEMBL522688 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H34F6N2O2 |
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| Mol. Mass. | 508.5401 |
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| SMILES | CCC1COCCC1N[C@@H]1CC[C@](C1)(C(C)C)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F |r| |
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| Structure | 
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