| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 8 |
|---|
| Ligand | BDBM50105690 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_900186 (CHEMBL3047468) |
|---|
| IC50 | 900±n/a nM |
|---|
| Citation |  TBA Med Chem Res21:568-577 (2012) Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 8 |
|---|
| Name: | Histone deacetylase 8 |
|---|
| Synonyms: | HD8 | HDAC8 | HDAC8_HUMAN | HDACL1 | Histone deacetylase 8 (HDAC-8) | Human HDAC8 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41749.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9BY41 |
|---|
| Residue: | 377 |
|---|
| Sequence: | MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPK
VASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATI
TAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLH
HGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKY
YQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPH
RIQQILNYIKGNLKHVV
|
|
|
|---|
| BDBM50105690 |
|---|
| n/a |
|---|
| Name | BDBM50105690 |
|---|
| Synonyms: | 2-(4-Benzenesulfonylamino-phenyl)-N-hydroxy-acetamide | CHEMBL319248 | N-hydroxy-2-(4-(phenylsulfonamido)phenyl)acetamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H14N2O4S |
|---|
| Mol. Mass. | 306.337 |
|---|
| SMILES | ONC(=O)Cc1ccc(NS(=O)(=O)c2ccccc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
