Reaction Details | |||
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Target | Tyrosine-protein phosphatase non-receptor type 1 | ||
Ligand | BDBM50246743 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_912278 (CHEMBL3055898) | ||
IC50 | 620±n/a nM | ||
Citation | TBA Med Chem Res21:351-361 (2012) Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Tyrosine-protein phosphatase non-receptor type 1 | |||
Name: | Tyrosine-protein phosphatase non-receptor type 1 | ||
Synonyms: | PTN1_HUMAN | PTP1B | PTPN1 | Protein tyrosine phosphatase 1B (PTP1B) | Protein tyrosine phosphatase-1B (PTP1B) | Protein-tyrosine phosphatase 1B | Protein-tyrosine phosphatase 1B (PTP1B) | Tyrosine-protein phosphatase non-receptor type 1 | Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) | ||
Type: | Protein phosphatase | ||
Mol. Mass.: | 49963.76 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Human recombinant GST-fusion PTP1B (1-435). | ||
Residue: | 435 | ||
Sequence: |
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BDBM50246743 | |||
n/a | |||
Name | BDBM50246743 | ||
Synonyms: | (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-(3-carboxybenzyloxy)-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid | CHEMBL506556 | ||
Type | Small organic molecule | ||
Emp. Form. | C38H54O5 | ||
Mol. Mass. | 590.8324 | ||
SMILES | CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](OCc6cccc(c6)C(O)=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O |r,c:10| | ||
Structure |