| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Liver carboxylesterase |
|---|
| Ligand | BDBM50371969 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_916865 (CHEMBL3082113) |
|---|
| IC50 | 135±n/a nM |
|---|
| Citation |  Wheelock, CE; Severson, TF; Hammock, BD Synthesis of new carboxylesterase inhibitors and evaluation of potency and water solubility. Chem Res Toxicol14:1563-72 (2001) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Liver carboxylesterase |
|---|
| Name: | Liver carboxylesterase |
|---|
| Synonyms: | Carboxylesterase | EST1_PIG |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 62009.98 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | ChEMBL_427761 |
|---|
| Residue: | 566 |
|---|
| Sequence: | MWLLPLVLTSLASSATWAGQPASPPVVDTAQGRVLGKYVSLEGLAQPVAVFLGVPFAKPP
LGSLRFAPPQPAEPWSFVKNTTSYPPMCCQDPVVEQMTSDLFTNGKERLTLEFSEDCLYL
NIYTPADLTKRGRLPVMVWIHGGGLVLGGAPMYDGVVLAAHENVVVVAIQYRLGIWGFFS
TGDEHSRGNWGHLDQVAALHWVQENIANFGGDPGSVTIFGESAGGESVSVLVLSPLAKNL
FHRAISESGVALTVALVRKDMKAAAKQIAVLAGCKTTTSAVFVHCLRQKSEDELLDLTLK
MKFLTLDFHGDQRESHPFLPTVVDGVLLPKMPEEILAEKDFNTVPYIVGINKQEFGWLLP
TMMGFPLSEGKLDQKTATSLLWKSYPIANIPEELTPVATDKYLGGTDDPVKKKDLFLDLM
GDVVFGVPSVTVARQHRDAGAPTYMYEFQYRPSFSSDKKPKTVIGDHGDEIFSVFGFPLL
KGDAPEEEVSLSKTVMKFWANFARSGNPNGEGLPHWPMYDQEEGYLQIGVNTQAAKRLKG
EEVAFWNDLLSKEAAKKPPKIKHAEL
|
|
|
|---|
| BDBM50371969 |
|---|
| n/a |
|---|
| Name | BDBM50371969 |
|---|
| Synonyms: | CHEMBL270374 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H23F3OS |
|---|
| Mol. Mass. | 284.381 |
|---|
| SMILES | CCCCCCCCCCSCC(=O)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
